Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728312 | 0.88 | TP53 (0.46) | MAOBALDH1A1LMNATP53 | |
| SCHEMBL5728418 | 0.86 | TACR1 (0.36) | KDM1AMAOAMAOBALDH1A1LMNA | |
| SCHEMBL5740873 | 0.82 | HPGD (0.40) | KDM1ACTSSCTSKALDH1A1TP53 | |
| SCHEMBL5728175 | 0.75 | GAA (0.44) | ALDH1A1TP53 | |
| SCHEMBL5727635 | 0.72 | MAOB (0.41) | KDM1AMAOAMAOBALDH1A1LMNA | |
| SCHEMBL6285264 | 0.70 | CTSS (0.56) | CTSSCTSKLMNASRCEPHX2 | |
| SCHEMBL31456961 | 0.70 | CTSS (0.56) | CTSSCTSKLMNASRCEPHX2 | |
| SCHEMBL5739111 | 0.69 | AKT1 (0.41) | CTSS | |
| SCHEMBL3255000 | 0.69 | P2RX7 (0.43) | P2RX7ALDH1A1LMNAPKMTP53 | |
| SCHEMBL5727679 | 0.69 | RECQL (0.40) | KDM1AMAOBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651613-A1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | Aventis Pharmaceuticals, Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014555-A1 | 4,5-DIHYDRO-IMIDAZOLE AS P2X7 ION CHANNEL BLOCKERS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-02-17 | — | — | WO | disclosed |