SCHEMBL572861

SCHEMBL572861

COc1ccc(/C=C/C(=O)ON(C(C)O)C(C)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 2/20 0.57
LMNA P02545 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
HDAC3 O15379 2/20 0.56
HDAC1 Q13547 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC8 Q9BY41 2/20 0.56
HDAC6 Q9UBN7 2/20 0.56
THRB P10828 1/20 0.55
ATM Q13315 1/20 0.55
GSK3B P49841 2/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC4 P56524 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
HDAC9 Q9UKV0 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4669173 1.00 F3 (0.57) F3LMNATDP1HDAC3HDAC1
SCHEMBL5054344 0.85 TAS1R3 (0.55) MAPTKMT2ATAS1R3TAS1R1SMN1; SMN2
SCHEMBL15838 0.78 CA12 (0.71) F3LMNATDP1HDAC3HDAC1
SCHEMBL342878 0.78 CA12 (0.71) F3LMNATDP1HDAC3HDAC1
SCHEMBL1375342 0.78 GSK3B (0.59) F3LMNATDP1HDAC3HDAC1
SCHEMBL18121572 0.77 KMT2A (0.76) F3LMNATDP1HDAC3HDAC1
SCHEMBL1237222 0.77 GSK3B (0.73) F3LMNATDP1HDAC3HDAC1
SCHEMBL30105639 0.77 GSK3B (0.73) F3LMNATDP1HDAC3HDAC1
SCHEMBL1397478 0.77 GSK3B (0.73) F3LMNATDP1HDAC3HDAC1
Water SCHEMBL8001684 0.77 CA12 (0.69) F3LMNATDP1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1436 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130837-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME DOW SILICONES CORP (US) 2026-05-14 US claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
US-12514802-B2 Polymer/hydrophobic ester oil blend DOW SILICONES CORPORATION (US) 2026-01-06 US claimed
WO-2025216872-A1 UV ABSORBING COSMETIC COMPOSITIONS THAT EXHIBIT SUN PROTECTION FACTOR BOOSTING IN THE PRESENCE OF BIODEGRADABLE CELLULOSE ESTER MICROBEADS EASTMAN CHEMICAL COMPANY (US) 2025-10-16 WO claimed
EP-4093514-B1 AQUEOUS SUNCASE FORMULATION BASED ON SULFATED A CRYSTALLINE CELLULOSE SPF BOOSTER DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-06 EP claimed
EP-4590260-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME Dow Silicones Corporation (US) 2025-07-30 EP claimed
EP-4590261-A1 SUN CARE FORMULATION Rohm and Haas Company (US) 2025-07-30 EP claimed
US-12370134-B2 Personal care formulation DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-29 US claimed
CN-119894491-A Sun protection preparation 罗门哈斯公司 2025-04-25 CN claimed
CN-119894490-A SPF potentiators and sunscreen formulations containing same 美国陶氏有机硅公司 2025-04-25 CN claimed
EP-0358528-B1 Cosmetic composition UNILEVER PLC (GB) 1994-06-15 EP claimed
EP-0261812-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1991-08-14 EP claimed
EP-0358528-A2 Cosmetic composition UNILEVER PLC (GB) 1990-03-14 EP claimed
EP-0261812-A1 Cosmetic composition UNILEVER PLC (GB) 1988-03-30 EP claimed
US-4731242-A Waterproof sunscreen compositions PALINCZAR VICTOR (US) 1988-03-15 US claimed
US-4710371-A BUTENE POLYMER AND ULTRAVIOLET RADIATION ABSORBER PALINCZAR VICTOR (US) 1987-12-01 US claimed
US-4699779-A Waterproof sunscreen compositions PALINCZAR VICTOR 1987-10-13 US claimed
US-4686099-A Aerosol waterproof sunscreen compositions CHESEBROUGH-POND'S INC. 1987-08-11 US claimed
US-4671956-A STABILITY; SIDE EFFECT REDUCTION L'OREAL (FR) 1987-06-09 US claimed
US-4671955-A ETHYL HYDROXYETHYL CELLULOSE AND AN ULTRAVIOLET RADIATION ABSORBER PALINCZAR VICTOR 1987-06-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370134-B2 Personal care formulation F12, C1R, MC1R F3 100/4885LMNA 2578/4885TDP1 915/4885
US-20260130837-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME SDC1, DSC1, SORD F3 2844/4885LMNA 2496/4885TDP1 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.