Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160069 | 1.00 | MTNR1A (0.50) | MTNR1AMTNR1BTAAR1MAOAPTGS1 | |
| Bromide SCHEMBL11719047 | 0.98 | MTNR1A (0.49) | MTNR1AMTNR1BTAAR1MAOAPTGS1 | |
| SCHEMBL9499616 | 0.92 | LTA4H (0.48) | MTNR1AMTNR1BMAOALTA4H | |
| SCHEMBL7582723 | 0.83 | MTNR1A (0.47) | MTNR1AMTNR1BTAAR1MAOAPTGS1 | |
| SCHEMBL9870637 | 0.81 | MTNR1A (0.53) | MTNR1AMTNR1BMAOAPTGS1LMNA | |
| SCHEMBL9870647 | 0.81 | MTNR1A (0.53) | MTNR1AMTNR1BMAOAPTGS1LMNA | |
| Methylamine SCHEMBL27820382 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1BMAOAPTGS1LMNA | |
| SCHEMBL9856089 | 0.80 | ACACB (0.40) | MTNR1AMTNR1BLTA4H | |
| SCHEMBL19286562 | 0.80 | TDP1 (0.47) | MTNR1AMTNR1BMAOAPOLB | |
| SCHEMBL20133454 | 0.80 | ACHE (0.41) | MTNR1AMTNR1BTAAR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |
| US-5672588-A | Purine derivatives | NOVO NORDISK A/S (DK) | 1997-09-30 | — | — | US | disclosed |
| EP-0603348-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993023418-A1 | PURINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-11-25 | — | — | WO | disclosed |