Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750823 | 0.75 | LMNA (0.33) | LMNAGAA | |
| SCHEMBL5729856 | 0.74 | CDC7 (0.41) | MAPK14 | |
| SCHEMBL5750632 | 0.71 | LMNA (0.43) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL5721981 | 0.71 | CDC7 (0.43) | ALDH1A1HTTMAPTKDM4ELMNA | |
| SCHEMBL4896548 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HTTMAPTKDM4ELMNA | |
| SCHEMBL27607456 | 0.69 | RARA (0.40) | ALDH1A1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL27607507 | 0.68 | RARA (0.41) | PTPN1PTPN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL29013103 | 0.67 | PTGS1 (0.33) | HTTKDM4ECYP1A2CYP2C19CYP2C9 | |
| SCHEMBL27511647 | 0.65 | HTT (0.44) | ALDH1A1HTTMAPTLMNAMEN1 | |
| SCHEMBL21834496 | 0.65 | CYP1A2 (0.44) | ALDH1A1MAPTLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |