Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MMP13 | P45452 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339441 | 0.85 | KDM4E (0.72) | MAPTGAAKDM4EHPGDALDH1A1 | |
| SCHEMBL29191009 | 0.80 | MEN1 (0.67) | MAPTMMP13KDM4EHPGDALDH1A1 | |
| SCHEMBL7011229 | 0.80 | LMNA (0.72) | GAAKDM4EHPGDALDH1A1LMNA | |
| SCHEMBL31061610 | 0.79 | MMP13 (1.00) | MMP13GAAKDM4EHPGDALDH1A1 | |
| SCHEMBL9416645 | 0.79 | MMP13 (0.94) | MMP13GAAKDM4EHPGDALDH1A1 | |
| SCHEMBL5332068 | 0.79 | MMP13 (1.00) | MMP13GAAKDM4EHPGDALDH1A1 | |
| SCHEMBL2576103 | 0.78 | KDM4E (0.74) | GAAKDM4ELMNA | |
| SCHEMBL3815151 | 0.78 | ALDH1A1 (0.72) | MAPTMMP13GAAKDM4EHPGD | |
| SCHEMBL7134254 | 0.78 | MMP13 (0.86) | MMP13KDM4EHPGDALDH1A1USP2 | |
| SCHEMBL660541 | 0.77 | MMP13 (0.70) | MMP13KDM4EHPGDALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691803-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056004-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |