Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961237 | 0.85 | LMNA (1.00) | KDM4ELMNAPOLBGAAKMT2A | |
| SCHEMBL15873902 | 0.85 | KDM4E (0.73) | KDM4ELMNAPOLBGAAHDAC2 | |
| SCHEMBL6917461 | 0.83 | KDM4E (0.69) | KDM4ELMNAPOLBGAAHDAC2 | |
| SCHEMBL3339441 | 0.82 | KDM4E (0.72) | KDM4ELMNAGAAKMT2A | |
| SCHEMBL29191107 | 0.82 | KDM4E (0.68) | KDM4ELMNAPOLBGAAHDAC2 | |
| SCHEMBL16740571 | 0.82 | KDM4E (0.72) | KDM4ELMNAPOLBGAAHDAC2 | |
| SCHEMBL7011229 | 0.82 | LMNA (0.72) | KDM4ELMNAPOLBGAA | |
| SCHEMBL3242636 | 0.79 | KDM4E (0.55) | KDM4ELMNAPOLBKMT2AHDAC2 | |
| SCHEMBL15873819 | 0.78 | KDM4E (0.63) | KDM4ELMNAPOLBGAAKMT2A | |
| SCHEMBL5731343 | 0.78 | MAPT (0.65) | KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-A2 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005121145-A2 | OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | claimed |
| US-10759765-B2 | Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute | CE PHARM CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20190127337-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | CE PHARM CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| EP-3444031-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017177979-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | 中国科学院上海有机化学研究所 | 2017-10-19 | — | — | WO | disclosed |
| EP-2382225-B1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GEN ELECTRIC (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2382225-B1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GEN ELECTRIC (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2382225-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | General Electric Company (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010074957-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074957-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100156278-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100156278-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100156278-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127337-A1 | HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE | AOC1, AOC2, AOC3 | KDM4E 3660/4885LMNA 4664/4885POLB 1801/4885 |
| US-20100156278-A1 | ORGANIC METAL COMPLEXES FOR USE IN OPTOELECTRONIC DEVICES | SCO2, C1S, C1R | KDM4E 4514/4885LMNA 4722/4885POLB 2560/4885 |
| US-10759765-B2 | Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute | AOC1, AOC2, AOC3 | KDM4E 3660/4885LMNA 4664/4885POLB 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.