SCHEMBL5733672

SCHEMBL5733672

CNNc1ccc(Br)cn1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.46
RAB9A P51151 9/20 0.45
NPC1 O15118 9/20 0.44
MAPK1 P28482 2/20 0.44
TP53 P04637 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
ATM Q13315 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30057293 0.84
SCHEMBL182965 0.84
Hydrochloric Acid SCHEMBL29168252 0.82 HCAR3 (0.47) FDPSRAB9ANPC1MAPK1TP53
SCHEMBL355054 0.78 ALDH1A1 (0.50) FDPSRAB9ANPC1MAPK1TP53
SCHEMBL2147165 0.77 RAB9A (0.49) FDPSRAB9ANPC1MAPK1TP53
SCHEMBL23394937 0.76 MKNK1 (0.39) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL6901316 0.76 FDPS (0.44) FDPSRAB9ANPC1MAPK1TP53
SCHEMBL24190662 0.76 PTK2 (0.53) FDPSRAB9ANPC1MAPK1TP53
SCHEMBL246507 0.74
SCHEMBL8503999 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070713-B1 QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2006-10-18 EP disclosed
US-6335447-B1 BACTERICIDES TOYAMA CHEMICAL CO., LTD. (JP) 2002-01-01 US disclosed
EP-1070713-A1 QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2001-01-24 EP disclosed