Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | FBP1 | P09467 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733870 | 1.00 | HSP90AA1 (0.60) | HSP90AA1FBP1ALDH1A1TDP1VCP | |
| SCHEMBL7313253 | 0.83 | HSP90AA1 (0.47) | HSP90AA1FBP1ALDH1A1TDP1RXRA | |
| SCHEMBL28594822 | 0.79 | RXRA (0.54) | HSP90AA1FBP1ALDH1A1TDP1VCP | |
| SCHEMBL798355 | 0.78 | RXRA (0.58) | HSP90AA1FBP1ALDH1A1RXRAPRMT1 | |
| SCHEMBL798354 | 0.78 | RXRA (0.58) | HSP90AA1FBP1ALDH1A1RXRAPRMT1 | |
| SCHEMBL20562379 | 0.77 | HSP90AA1 (0.45) | HSP90AA1FBP1ALDH1A1TDP1VCP | |
| SCHEMBL20562377 | 0.77 | HSP90AA1 (0.45) | HSP90AA1FBP1ALDH1A1TDP1VCP | |
| SCHEMBL19995993 | 0.75 | HSP90AA1 (0.60) | HSP90AA1FBP1VCPRXRA | |
| SCHEMBL8040118 | 0.75 | HSP90AA1 (1.00) | HSP90AA1FBP1ALDH1A1TDP1VCP | |
| SCHEMBL7414256 | 0.75 | HSP90AA1 (1.00) | HSP90AA1FBP1ALDH1A1TDP1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311471-B1 | PHENYL- AND PHENYLALKYL-SUBSTITUTED ETHANOLAMINES AND ETHYLENEDIAMINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-6770636-B2 | CENTRAL NERVOUS SYSTEM DISORDERS THERAPY | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20020042410-A1 | Phenyl-and phenylalkyl-substituted ethanolamines and ethylenediamines | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-11 | — | — | US | disclosed |
| WO-1988003147-A1 | SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1988-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042410-A1 | Phenyl-and phenylalkyl-substituted ethanolamines and ethylenediamines | AOC2, CYC1, CYCS | HSP90AA1 2112/4885FBP1 3644/4885ALDH1A1 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.