Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 4/20 | 0.40 |
| ▸ | TLR2 | O60603 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733864 | 0.83 | HSP90AA1 (0.60) | HSP90AA1FBP1ALDH1A1TDP1LMNA | |
| SCHEMBL5733870 | 0.83 | HSP90AA1 (0.60) | HSP90AA1FBP1ALDH1A1TDP1LMNA | |
| SCHEMBL6548166 | 0.76 | KDM4E (0.40) | ALDH1A1TDP1LMNAHPGDMAPK1 | |
| SCHEMBL27673733 | 0.75 | FBP1 (0.55) | HSP90AA1FBP1ALDH1A1TDP1MEN1 | |
| SCHEMBL30404870 | 0.74 | KDM4E (0.45) | ALDH1A1MEN1LMNAHPGDKMT2A | |
| SCHEMBL309416 | 0.74 | KDM4E (0.45) | ALDH1A1MEN1LMNAHPGDKMT2A | |
| SCHEMBL21981692 | 0.73 | MAOA (0.55) | LMNAHPGDSMN1; SMN2NPSR1TLR4 | |
| SCHEMBL21981693 | 0.73 | MAOA (0.55) | LMNAHPGDSMN1; SMN2NPSR1TLR4 | |
| SCHEMBL7313258 | 0.72 | RXRA (0.51) | HSP90AA1FBP1ALDH1A1MEN1S1PR4 | |
| SCHEMBL27463129 | 0.72 | KDM4E (0.42) | ALDH1A1TDP1LMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |