SCHEMBL57346

SCHEMBL57346

N#Cc1ccc(F)cc1F

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.61
CYP11B2 P19099 14/20 0.55
CYP11B1 P15538 13/20 0.55
AR P10275 1/20 0.47
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30919072 1.00 TRPV4 (0.61) TRPV4CYP11B2CYP11B1ARMAOA
SCHEMBL12496622 0.82 CYP11B2 (0.77) TRPV4CYP11B2CYP11B1
SCHEMBL573864 0.82 MAOB (0.53) TRPV4CYP11B2CYP11B1ARMAOA
Dichlobenil SCHEMBL4715206 0.82 TRPV4 (0.44) TRPV4CYP11B2CYP11B1ARALDH1A1
SCHEMBL52204 0.81 TRPV4 (0.47) TRPV4CYP11B2CYP11B1ARMAOA
SCHEMBL18297999 0.80 CYP11B2 (0.67) TRPV4CYP11B2CYP11B1
SCHEMBL21131569 0.80 TRPV4 (0.45) TRPV4CYP11B2CYP11B1ARMAOA
SCHEMBL74807 0.80 TRPV4 (0.46) TRPV4CYP11B2CYP11B1ARMAOA
SCHEMBL3245685 0.79 ALDH1A1 (0.46) TRPV4CYP11B2CYP11B1ALDH1A1
Ethylene SCHEMBL27960950 0.78 MAOB (0.50) TRPV4CYP11B2CYP11B1ARMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
CN-112410380-B Preparation method of 2, 4-difluorobenzylamine 弈柯莱生物科技(集团)股份有限公司 2025-06-13 CN claimed
CN-120028308-A Small molecule Raman probe, bar code probe, encoding method and application thereof 北京大学 2025-05-23 CN claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-119219522-A Preparation method of 2, 4-difluorobenzonitrile 广西鲲宇药业有限公司 2024-12-31 CN claimed
CN-114276266-B Preparation method of 4-amino-2-fluorobenzamide 兰州康鹏威耳化工有限公司 2024-10-11 CN claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-118315670-A Electrolyte additive and application thereof, single-particle graphite negative electrode electrolyte and application thereof 国网湖南省电力有限公司 2024-07-09 CN claimed
EP-3898595-B1 PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS MERCK SHARP & DOHME LLC (US) 2024-05-01 EP claimed
EP-0459332-A2 Process for producing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-12-04 EP claimed
EP-0429964-A2 Polyether copolymers, a method of producing them, resin compositions containing them, and molded articles formed from them IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-06-05 EP claimed
EP-0243000-B1 POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-03 EP claimed
EP-0186153-B1 PROCESS FOR PREPARING POLYCYANOARYL ETHER POWDER IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-07-25 EP claimed
US-4822903-A Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-04-18 US claimed
EP-0243000-A1 Polycyanoaryl ether, method for preparing the same and uses thereof IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-10-28 EP claimed
US-4663427-A Process for preparing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-05-05 US claimed
EP-0186153-A2 Process for preparing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1986-07-02 EP claimed
US-4438042-A FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-03-20 US claimed
US-4436669-A CYANATION, DECARBONYLATION, ACID CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-03-13 US claimed