SCHEMBL573864

SCHEMBL573864

N#Cc1ccc(F)cc1C#N

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.53
MAOA P21397 9/20 0.53
TRPV4 Q9HBA0 2/20 0.46
AR P10275 1/20 0.45
CYP11B2 P19099 3/20 0.43
CYP11B1 P15538 2/20 0.43
SLC22A12 Q96S37 1/20 0.40
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL27960950 0.95 MAOB (0.50) MAOBMAOATRPV4ARCYP11B2
SCHEMBL16957602 0.86 MAOA (0.43) MAOBMAOATRPV4ARCYP11B2
SCHEMBL2131318 0.83 ALDH1A1 (0.61) ARSLC22A12KDM4EUSP2ALDH1A1
SCHEMBL10085517 0.83 AR (0.45) MAOBMAOATRPV4ARCYP11B2
SCHEMBL57346 0.82 TRPV4 (0.61) MAOBMAOATRPV4ARCYP11B2
SCHEMBL30919072 0.82 TRPV4 (0.61) MAOBMAOATRPV4ARCYP11B2
SCHEMBL21116203 0.82 USP8 (0.42) MAOBMAOATRPV4CYP11B2CYP11B1
SCHEMBL21131569 0.82 TRPV4 (0.45) MAOBMAOATRPV4ARCYP11B2
SCHEMBL74807 0.82 TRPV4 (0.46) MAOBMAOATRPV4ARCYP11B2
SCHEMBL17827370 0.81 CYP11B2 (0.59) MAOBMAOAARCYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330339-A Method for preparing porous carbon based on synchronous synthesis of nitrile resin/graphene nanosheets and porous carbon material 成都大学 2025-01-21 CN claimed
CN-114512719-B Eutectic solvent-based electrolyte and application thereof 中国科学院青岛生物能源与过程研究所 2024-12-03 CN claimed
CN-117855377-A Composite pole piece, preparation method and application thereof, and low-temperature lithium ion battery 中科超能(深圳)新能源科技有限公司 2024-04-09 CN claimed
CN-117673467-A Electrolyte and battery comprising same 珠海冠宇电池股份有限公司 2024-03-08 CN claimed
CN-114512719-A Eutectic solvent-based electrolyte and application thereof 中国科学院青岛生物能源与过程研究所 2022-05-17 CN claimed
CN-110628049-B Photoresponse antibacterial self-repairing collagen gel and preparation method thereof 西华师范大学 2022-04-12 CN claimed
CN-111875794-A Novel preparation method of nitrile resin monomer 成都大学 2020-11-03 CN claimed
CN-106898813-B Solid electrolyte, solid electrolyte membrane and manufacturing method thereof, and lithium secondary battery 上海交通大学 2020-07-31 CN claimed
CN-108929297-B Dianhydride monomer containing asymmetric fluorophore structure and preparation method and application thereof 吉林大学 2020-03-31 CN claimed
CN-110628049-A Photoresponse antibacterial self-repairing collagen gel and preparation method thereof 西华师范大学 2019-12-31 CN claimed
CN-108475819-A Solid electrolyte, solid electrolyte membrane and method for producing same, and secondary battery 上海交通大学 2018-08-31 CN claimed
US-12364160-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2025-07-15 US disclosed
CN-120077108-A Compounds of formula (I) 住友化学株式会社 2025-05-30 CN disclosed
CN-120035640-A Coloring agent 住友化学株式会社 2025-05-23 CN disclosed
US-20250136620-A1 BTK DEGRADER NEWAVE PHARMACEUTICAL INC. 2025-05-01 US disclosed
EP-0244780-B1 Photoconductive phthalocyanine pigments, electrophotographic elements containing them, and a method of use EASTMAN KODAK CO (US) 1995-01-11 EP disclosed
US-5238764-A Photosensitivity EASTMAN KODAK COMPANY (US) 1993-08-24 US disclosed
US-5238766-A Coating compositions containing a titanyl fluorophthalocyanine pigment EASTMAN KODAK COMPANY (US) 1993-08-24 US disclosed
EP-0244780-A2 Photoconductive phthalocyanine pigments, electrophotographic elements containing them, and a method of use EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-11-11 EP disclosed
US-4701396-A ELECTROSTATIC CHANGING, EXPOSURE TO PATTERN OF INFRARED RADIATION, AND DEVELOPMENT EASTMAN KODAK COMPANY (US) 1987-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12364160-B2 Organic electroluminescent element and electronic device RPL21, RPS21, RPL19 MAOB 2740/4885MAOA 2657/4885TRPV4 669/4885
US-20250136620-A1 BTK DEGRADER BTK, CBL, LYN MAOB 2501/4885MAOA 2582/4885TRPV4 4395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.