Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634117 | 0.79 | LIPE (0.34) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL10171866 | 0.77 | LIPE (0.33) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL27805998 | 0.77 | HSP90AA1 (0.34) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL612354 | 0.77 | L3MBTL1 (0.44) | PKMKMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL5807215 | 0.77 | LIPE (0.33) | LIPEPKMKMT2APOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL3319581 | 0.76 | L3MBTL1 (0.43) | PKMKMT2AALDH1A1TSHRUSP2 | |
| SCHEMBL158497 | 0.74 | TSHR (0.55) | KMT2APOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12012145 | 0.73 | LIPE (0.36) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL304030 | 0.72 | LIPE (0.41) | LIPETSHRSMN1; SMN2 | |
| SCHEMBL31028 | 0.72 | USP2 (0.56) | KMT2AALDH1A1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538088-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V Biosciences, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| EP-1716127-A2 | GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082871-A2 | GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2005-09-09 | — | — | WO | disclosed |