Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634117 | 0.79 | LIPE (0.34) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL612354 | 0.77 | L3MBTL1 (0.44) | PKMKMT2AALDH1A1 | |
| SCHEMBL27805998 | 0.77 | HSP90AA1 (0.34) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL5807215 | 0.77 | LIPE (0.33) | LIPEPKMKMT2APOLBALDH1A1 | |
| SCHEMBL5734834 | 0.77 | LIPE (0.37) | LIPEPKMKMT2APOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL3319581 | 0.76 | L3MBTL1 (0.43) | PKMKMT2AALDH1A1 | |
| SCHEMBL12331158 | 0.75 | — | — | |
| SCHEMBL158497 | 0.74 | TSHR (0.55) | KMT2APOLBALDH1A1 | |
| SCHEMBL10863945 | 0.74 | LIPE (0.39) | LIPEMGLL | |
| Iodomethane SCHEMBL15848230 | 0.74 | USP2 (0.53) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | LIPE 3000/4885PKM 4251/4885KMT2A 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.