Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR5A | P47898 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961623 | 0.84 | MAPT (0.62) | GPR55SMN1; SMN2MAPTNFKB1MAPK1 | |
| SCHEMBL7966843 | 0.80 | CYP2D6 (0.63) | HTR1AGPR55SMN1; SMN2MAPTNFKB1 | |
| SCHEMBL17115053 | 0.79 | FAAH (0.48) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL3759275 | 0.77 | HTR7 (1.00) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL30022433 | 0.77 | HTR7 (1.00) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| Hydrochloric Acid SCHEMBL1673713 | 0.76 | HTR7 (0.96) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL5736286 | 0.73 | MAPT (0.53) | GPR55SMN1; SMN2MAPTNFKB1MAPK1 | |
| SCHEMBL2244692 | 0.73 | ALDH1A1 (0.51) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL12083807 | 0.72 | SMN1; SMN2 (0.60) | GPR55SMN1; SMN2MAPTNFKB1MAPK1 | |
| Hydrochloric Acid SCHEMBL2247573 | 0.71 | ALDH1A1 (0.50) | HTR7HTR1AHTR2AHTR5AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934288-B1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |
| EP-0934288-A1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017652-A1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-04-30 | — | — | WO | disclosed |