Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736286 | 0.89 | MAPT (0.53) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL5734895 | 0.84 | HTR7 (0.61) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL7966843 | 0.82 | CYP2D6 (0.63) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL17987100 | 0.77 | HTR1A (0.62) | MAPTMAPK1KMT2ALMNAHRH4 | |
| SCHEMBL5734066 | 0.74 | MAPT (0.55) | MAPTGPR55ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7947523 | 0.74 | MAPT (0.54) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL12083807 | 0.72 | SMN1; SMN2 (0.60) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL7399348 | 0.71 | GPR55 (0.71) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL7961948 | 0.71 | GPR55 (0.65) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL7959021 | 0.70 | MAPT (0.50) | MAPTGPR55ALDH1A1SMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |