Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600544 | 0.84 | KIF11 (0.41) | AKR1C2CYP2D6NOTUMNPC1TP53 | |
| SCHEMBL4951261 | 0.83 | KIF11 (0.35) | PTPN5AKR1C3AKR1C2NPC1TP53 | |
| SCHEMBL7647650 | 0.83 | MEN1 (0.35) | NOTUMNPC1RAB9A | |
| SCHEMBL5521594 | 0.81 | TSHR (0.45) | NPC1RAB9ANPSR1 | |
| SCHEMBL3816568 | 0.81 | PTPN5 (0.37) | PTPN5AKR1C3AKR1C2CYP2D6CYP2C9 | |
| SCHEMBL6494848 | 0.80 | LMNA (0.36) | PTPN5CYP2C9HIF1ATNKSPARP1 | |
| SCHEMBL6535998 | 0.80 | MEN1 (0.38) | AKR1C3AKR1C2CYP2C9TP53 | |
| SCHEMBL9598451 | 0.79 | RXRA (0.42) | NPC1RAB9A | |
| SCHEMBL9600261 | 0.79 | KCNH2 (0.36) | TNKSPARP1TNKS2NPC1RAB9A | |
| SCHEMBL9600296 | 0.79 | ALDH1A1 (0.31) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105375-B1 | TRIFLUOROMETHYLPYRROLCARBOXAMIDES USEFUL AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-22 | — | — | EP | disclosed |
| US-6365620-B2 | Trifluoromethylpyrrolcarboxamides | SYNGENTA CROP PROTECTION, INC. | 2002-04-02 | — | — | US | disclosed |
| US-20020019541-A1 | Trifluoromethylpyrrolcarboxamides | EBERLE MARTIN (CH) | 2002-02-14 | — | — | US | disclosed |
| EP-1105375-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | Syngenta Participations AG (CH) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009482-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019541-A1 | Trifluoromethylpyrrolcarboxamides | CBR3, CBR1, DDT | PTPN5 2878/4885AKR1C3 493/4885AKR1C2 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.