Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599913 | 0.91 | THRB (0.36) | NOTUMALDH1A1RAB9ANPSR1KDM4E | |
| SCHEMBL564584 | 0.89 | LMNA (0.34) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL1369636 | 0.86 | RXRA (0.38) | LMNATNKSPARP1TNKS2HDAC6 | |
| SCHEMBL15067062 | 0.85 | LMNA (0.38) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL5868259 | 0.84 | TSHR (0.34) | NOTUMALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL4951261 | 0.84 | KIF11 (0.35) | LMNAALDH1A1HTTNPC1RAB9A | |
| SCHEMBL8095649 | 0.83 | MAPT (0.34) | NOTUMTNKSPARP1TNKS2HDAC6 | |
| SCHEMBL5887096 | 0.81 | LMNA (0.34) | LMNATRPA1PTGS1CACNA1CHPGD | |
| SCHEMBL2724725 | 0.81 | NPC1 (0.35) | NPC1RAB9ANISCHMAPT | |
| SCHEMBL9753779 | 0.81 | RXRA (0.44) | ALDH1A1HTTALOX12TP53TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288258-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | DIANA GUY D | 2005-12-29 | — | — | US | disclosed |
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288258-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | MAVS, HAVCR2, ZC3HAV1 | LMNA 1196/4885TRPA1 3808/4885PTGS1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.