Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736316 | 0.81 | MAOB (0.51) | L3MBTL1MAOBLMNAKDM4EALOX15 | |
| SCHEMBL5735956 | 0.80 | MAOB (0.54) | L3MBTL1MAOBLMNAKDM4EALOX15 | |
| SCHEMBL12434732 | 0.74 | L3MBTL1 (0.56) | L3MBTL1MAOBLMNAKDM4EALOX15 | |
| SCHEMBL7193788 | 0.74 | L3MBTL1 (0.56) | L3MBTL1MAOBLMNAKDM4EALOX15 | |
| SCHEMBL6551819 | 0.74 | L3MBTL1 (0.52) | L3MBTL1MAOBMEN1KMT2A | |
| SCHEMBL375324 | 0.73 | LMNA (0.43) | KCNH2LMNAGAA | |
| SCHEMBL30271547 | 0.73 | LMNA (0.43) | KCNH2LMNAGAA | |
| SCHEMBL9625233 | 0.72 | L3MBTL1 (0.54) | L3MBTL1MAOBKDM4EGAAMEN1 | |
| SCHEMBL12074443 | 0.72 | L3MBTL1 (0.54) | L3MBTL1MAOBKDM4EMEN1KMT2A | |
| SCHEMBL22639882 | 0.72 | LMNA (0.70) | LMNAKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311471-B1 | PHENYL- AND PHENYLALKYL-SUBSTITUTED ETHANOLAMINES AND ETHYLENEDIAMINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2006-04-12 | — | — | EP | disclosed |