Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945158 | 0.87 | L3MBTL1 (0.54) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL9263396 | 0.85 | ESR2 (0.62) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL9853813 | 0.84 | KMT2A (0.49) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL2013294 | 0.84 | KMT2A (0.55) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL8076951 | 0.84 | L3MBTL1 (0.62) | L3MBTL1HPGDKMT2APOLBALDH1A1 | |
| SCHEMBL29550783 | 0.83 | L3MBTL1 (0.56) | L3MBTL1HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL5708950 | 0.82 | LMNA (0.60) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL39472 | 0.82 | HPGD (0.78) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL12142560 | 0.81 | MAPT (0.58) | L3MBTL1HPGDKMT2APOLBMEN1 | |
| SCHEMBL29186599 | 0.81 | ALDH1A1 (0.55) | L3MBTL1HPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660454-A1 | AZACYCLIC COMPOUNDS AS INHIBITORS OF SENSORY NEURONE SPECIFIC CHANNELS | Vernalis (R&D) Limited (GB) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005005392-A1 | AZACYCLIC COMPOUNDS AS INHIBITORS OF SENSORY NEURONE SPECIFIC CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |