Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853809 | 0.87 | KMT2A (0.50) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL5739618 | 0.84 | L3MBTL1 (0.61) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL8560647 | 0.78 | HTT (0.50) | KMT2AL3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9853829 | 0.77 | LMNA (0.45) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL2013294 | 0.76 | KMT2A (0.55) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL27972730 | 0.76 | MAPT (0.49) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL9853818 | 0.76 | MAPT (0.47) | KMT2AL3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL5708950 | 0.74 | LMNA (0.60) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL12672297 | 0.74 | HTT (0.45) | KMT2AL3MBTL1MEN1POLBMAPT | |
| SCHEMBL9853798 | 0.73 | TDP1 (0.54) | KMT2AL3MBTL1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |