Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741345 | 0.82 | RARB (0.40) | XDHALDH1A1 | |
| SCHEMBL6509167 | 0.79 | ALDH1A1 (0.38) | XDHALDH1A1 | |
| SCHEMBL5741091 | 0.78 | BRD4 (0.35) | BRD4CDKN1AALDH1A1 | |
| SCHEMBL5741718 | 0.71 | SMN1; SMN2 (0.44) | ALDH1A1 | |
| SCHEMBL5741304 | 0.71 | HSD17B10 (0.44) | BRD4ALDH1A1 | |
| SCHEMBL6659146 | 0.70 | RNASEL (0.48) | BRD4 | |
| SCHEMBL5738977 | 0.68 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL6689643 | 0.66 | ABCC1 (0.41) | ALDH1A1 | |
| SCHEMBL29292345 | 0.66 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL5740682 | 0.65 | PTGS2 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406891-B1 | THIOCHROMENONES USED TO COMBAT PAINFUL CONDITIONS AND NEURODEGENERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20050009820-A1 | Thiochromenones used to combat painful conditions and neurodegenerative diseases | BAYER HEALTHCARE AG (DE) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009820-A1 | Thiochromenones used to combat painful conditions and neurodegenerative diseases | HTT, HMOX1, SNCA | XDH 1226/4885BRD4 2633/4885CDKN1A 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.