SCHEMBL574158

SCHEMBL574158

OC(=Cc1ccccc1)c1c(O)c(O)c(O)c(O)c1O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.40
TTR P02766 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
FBP1 P09467 3/20 0.38
TRPA1 O75762 1/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
PRMT1 Q99873 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18109191 0.81 CA2 (0.44) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL1647472 0.74 ALDH1A1 (0.44) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL918848 0.74 AKR1C1 (0.54) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL389392 0.74 AKR1C1 (0.54) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL368124 0.74 AKR1C1 (0.54) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL19953569 0.71 MAOB (0.53) ESR1ALDH1A1TSHRTRPA1CYP3A4
SCHEMBL19668043 0.70 CA1 (0.52) ALDH1A1TSHRTRPA1CYP3A4
SCHEMBL29253620 0.69 ALDH1A1 (0.50) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL131223 0.69 MAOB (0.53) ESR1ALDH1A1TSHRAKR1C3AKR1C1
SCHEMBL2505599 0.69 TSHR (0.41) ESR1ALDH1A1TSHRAKR1C3TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024238399-A1 METHODS OF MANUFACTURING ADENO-ASSOCIATED VIRAL VECTORS SIREN BIOTECHNOLOGY, INC. (US) 2024-11-21 WO claimed
EP-4427758-A1 NEW SYNERGISTIC ANTI-INFLAMMATORY, ANTIOXIDANT AND ANTIBACTERIAL ASSOCIATION NOOS S.r.l. (IT) 2024-09-11 EP claimed
US-20230141224-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FIGENE, LLC 2023-05-11 US claimed
EP-4142751-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) Figene, LLC (US) 2023-03-08 EP claimed
WO-2021202032-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FIGENE, LLC (US) 2021-10-07 WO claimed
EP-4678169-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF INFECTIONS WITH RSV Szekeres, Thomas (AT) 2026-01-14 EP disclosed
EP-4516298-A1 STILBENE COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF INFECTIONS WITH CYTOMEGALOVIRUS (CMV) Szekeres, Thomas (AT) 2025-03-05 EP disclosed
EP-4313010-B1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 SZEKERES THOMAS (AT) 2025-02-19 EP disclosed
WO-2024238399-A1 METHODS OF MANUFACTURING ADENO-ASSOCIATED VIRAL VECTORS SIREN BIOTECHNOLOGY, INC. (US) 2024-11-21 WO disclosed
EP-4427758-A1 NEW SYNERGISTIC ANTI-INFLAMMATORY, ANTIOXIDANT AND ANTIBACTERIAL ASSOCIATION NOOS S.r.l. (IT) 2024-09-11 EP disclosed
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds SZEKERES THOMAS (AT) 2024-05-23 US disclosed
EP-4313010-A1 COMPOUNDS FOR USE IN THE TREATMENT AND PREVENTION OF COVID- 19 Szekeres, Thomas (AT) 2024-02-07 EP disclosed
WO-2012017451-A1 A BIO-STABILIZED RESVERATROL FORMULATION KHANDELWAL SANJEEV (IN) 2012-02-09 WO disclosed
EP-1654210-B1 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2008-07-30 EP disclosed
US-20070191627-A1 Stilbene derivatives and their use in medicaments SZEKERES THOMAS 2007-08-16 US disclosed
WO-2007002973-A2 USE OF STILBENE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF SOLID TUMOURS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2007-01-11 WO disclosed
EP-1654210-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS Szekeres, Thomas (AT) 2006-05-10 EP disclosed
WO-2005102298-A1 MEDICAL SUBSTANCE MIXTURES CONTAINING RESVERATROL OR RESVERATROL-DERIVATIVES, IN ADDITION TO THE USE THEREOF IN THE PRODUCTION OF MEDICAMENTS SZEKERES THOMAS (AT) 2005-11-03 WO disclosed
WO-2005016860-A2 STILBENE DERIVATIVES AND THEIR USE IN MEDICAMENTS SZEKERES THOMAS (AT) 2005-02-24 WO disclosed
EP-1068864-A1 Use of at least a hydroxystilbene as a glycation inhibitor L'OREAL (FR) 2001-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166587-A1 SARS-CoV-2 inhibitors - artificial compounds ACE2, ACE, FURIN ESR1 833/4885ALDH1A1 2822/4885TSHR 3012/4885
US-20070191627-A1 Stilbene derivatives and their use in medicaments PTGS2, PTGS1, PTGER2 ESR1 330/4885ALDH1A1 333/4885TSHR 3183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.