SCHEMBL1647472

SCHEMBL1647472

OC(=Cc1ccccc1)c1ccccc1C(O)=Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C1 Q04828 1/20 0.43
ESR1 P03372 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
FBP1 P09467 3/20 0.40
ALOX15 P16050 1/20 0.39
MAOB P27338 1/20 0.39
CYP2A6 P11509 1/20 0.39
DHODH Q02127 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
PRMT1 Q99873 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19953569 0.85 MAOB (0.53) ALDH1A1TSHRESR1MEN1KMT2A
SCHEMBL918848 0.78 AKR1C1 (0.54) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL368124 0.78 AKR1C1 (0.54) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL389392 0.78 AKR1C1 (0.54) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL574158 0.74 ESR1 (0.45) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL3868848 0.74 MCL1 (0.44) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL7715071 0.74 TSHR (0.52) ALDH1A1TSHRAKR1C3ESR1MEN1
SCHEMBL18543084 0.74 MCL1 (0.44) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL29253620 0.73 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL131223 0.73 MAOB (0.53) ALDH1A1TSHRAKR1C3AKR1C1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3349863-B1 FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER JOHNSON & JOHNSON CONSUMER INC (US) 2022-01-19 EP claimed
CN-108025197-B Foaming sunscreen compositions containing UV radiation absorbing compounds and superhydrophilic amphiphilic copolymers 强生消费者公司 2021-09-07 CN claimed
CN-108112232-B Sunscreen compositions comprising superhydrophilic amphiphilic copolymers 强生消费者公司 2021-08-10 CN claimed
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC. 2011-08-11 US claimed
CN-106619147-B Effervescent sunscreen compositions 强生消费者公司 2022-07-29 CN disclosed
CN-108025197-B Foaming sunscreen compositions containing UV radiation absorbing compounds and superhydrophilic amphiphilic copolymers 强生消费者公司 2021-09-07 CN disclosed
CN-108112232-B Sunscreen compositions comprising superhydrophilic amphiphilic copolymers 强生消费者公司 2021-08-10 CN disclosed
US-8475774-B2 Sunscreen compositions comprising an ultraviolet radiation-absorbing polymer JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-07-02 US disclosed
US-8075930-B2 Extracts of Phyllanthus niruri JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2011-12-13 US disclosed
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER JOHNSON & JOHNSON CONSUMER INC. 2011-08-11 US disclosed
US-20110081432-A1 EXTRACTS OF PHYLLANTHUS NIRURI JOHNSON & JOHNSON CONSUMER INC. 2011-04-07 US disclosed
US-20100129299-A1 TOPICAL SUNSCREEN COMPOSITIONS FOR MITIGATING EFFECTS ON INTRACELLULAR ION CONCENTRATION NEUTROGENA CORPORATION 2010-05-27 US disclosed
US-5698183-A MODIFIED POLYESTER OR POLYAMIDE; SUNSCREEN AGENT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-12-16 US disclosed
WO-1993022413-A1 COMPOSITIONS COMPRISING WATER-DISPERSIBLE COPOLYMER CONTAINING UVA AND UVB LIGHT-ABSORBING MONOMERS UNILEVER PLC (GB) 1993-11-11 WO disclosed
WO-1993022366-A1 WATER-DISPERSIBLE COPOLYMER CONTAINING UVA AND UVB LIGHT-ABSORBING MONOMERS UNILEVER PLC (GB) 1993-11-11 WO disclosed
US-5250652-A High loading water-dispersible UVA and/or UVB light-absorbing copolymer LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-10-05 US disclosed
US-5243021-A Polylactam, polyester, polyether copolymers containing stilbene groups LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195036-A1 SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER ERCC1, MMS19, ERCC5 ALDH1A1 1416/4885TSHR 4483/4885AKR1C3 3354/4885
US-20100129299-A1 TOPICAL SUNSCREEN COMPOSITIONS FOR MITIGATING EFFECTS ON INTRACELLULAR ION CONCENTRATION NUDT1, SUN2, SLC29A2 ALDH1A1 1468/4885TSHR 4111/4885AKR1C3 1925/4885
US-20110081432-A1 EXTRACTS OF PHYLLANTHUS NIRURI CUTA, COLGALT1, COL1A1 ALDH1A1 705/4885TSHR 4484/4885AKR1C3 2733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.