Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.46 |
| ▸ | VNN1 | O95497 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.43 |
| ▸ | BCR | P11274 | 3/20 | 0.43 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742550 | 1.00 | MKNK1 (0.46) | MKNK1MKNK2VNN1AVPR2OXTR | |
| SCHEMBL5742551 | 0.90 | HPGD (0.46) | ALDH1A1 | |
| SCHEMBL4936854 | 0.85 | OXTR (0.46) | MKNK1MKNK2VNN1AVPR2OXTR | |
| SCHEMBL5744591 | 0.78 | ALDH1A1 (0.53) | MKNK1MKNK2AVPR2OXTRAVPR1A | |
| SCHEMBL5744595 | 0.78 | ALDH1A1 (0.53) | MKNK1MKNK2AVPR2OXTRAVPR1A | |
| SCHEMBL5741564 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1HTR2B | |
| SCHEMBL5741557 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1HTR2B | |
| SCHEMBL4944302 | 0.75 | OXTR (0.45) | VNN1OXTRAVPR1AGHSR | |
| SCHEMBL4944097 | 0.75 | OXTR (0.54) | OXTRAVPR1AALDH1A1 | |
| SCHEMBL31700370 | 0.71 | VNN1 (0.66) | VNN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | claimed |