Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540979 | 0.87 | MAPK14 (0.35) | MAPK14RBP4SMN1; SMN2 | |
| SCHEMBL3547829 | 0.84 | MAPK14 (0.35) | MAPK14RBP4SMN1; SMN2 | |
| SCHEMBL5743114 | 0.83 | ENPP2 (0.34) | MAPK14RBP4SMN1; SMN2PTGDR2DRD4 | |
| SCHEMBL3538233 | 0.83 | DRD4 (0.35) | MAPK14LMNATP53MAPTTHRB | |
| SCHEMBL3544775 | 0.82 | HTR1A (0.40) | LMNAMAPTRBP4PTGDR2ALDH1A1 | |
| SCHEMBL5742487 | 0.82 | DRD4 (0.33) | MAPK14LMNATP53MAPTTHRB | |
| SCHEMBL5742412 | 0.81 | HTR1A (0.38) | LMNATP53RBP4 | |
| SCHEMBL3543682 | 0.81 | NPSR1 (0.36) | MAPK14MAPTRBP4SMN1; SMN2PTGDR2 | |
| SCHEMBL3546483 | 0.81 | LMNA (0.36) | MAPK14LMNATP53MAPTTHRB | |
| SCHEMBL3544303 | 0.81 | RBP4 (0.41) | MAPK14MAPTRBP4SMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |