Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742628 | 0.82 | MAPK14 (0.37) | DRD4RBP4MAPK14MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL5742485 | 0.80 | SLC6A4 (0.39) | — | |
| SCHEMBL5744423 | 0.80 | KDM4E (0.44) | RBP4MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3540439 | 0.78 | DRD4 (0.38) | DRD4RBP4MAPTLMNATP53 | |
| SCHEMBL5743114 | 0.78 | ENPP2 (0.34) | DRD4RBP4GPR119MAPK14KDM4E | |
| SCHEMBL3540773 | 0.75 | RBP4 (0.40) | RBP4MAPTLMNADRD2 | |
| SCHEMBL3543078 | 0.75 | HTR1A (0.45) | MAPK14 | |
| SCHEMBL5742981 | 0.73 | RBP4 (0.37) | DRD4RBP4MAPTLMNATP53 | |
| SCHEMBL12883607 | 0.73 | GPR119 (0.46) | GPR119MAPTLMNATP53THRB | |
| SCHEMBL3543682 | 0.71 | NPSR1 (0.36) | DRD4RBP4MAPK14MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |