SCHEMBL574263

SCHEMBL574263

C[C@H](NC(=O)[C@@H](C)N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.52
MME P08473 4/20 0.48
ACE P12821 1/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
CTRB1 P17538 5/20 0.42
DPP8 Q6V1X1 1/20 0.40
DPP7 Q9UHL4 1/20 0.40
SLC7A5 Q01650 1/20 0.40
LTA4H P09960 2/20 0.40
RAB9A P51151 1/20 0.39
PAX8 Q06710 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17545410 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL380599 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL5161799 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL29898350 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL380600 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL9698824 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL476353 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL159553 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL159552 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
Water SCHEMBL23711627 0.98 DPP4 (0.50) DPP4MMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
EP-4684807-A1 LINKER AND USE THEREOF IN LIGAND DRUG CONJUGATE Duality Biologics (Shanghai) Co., Ltd. (CN) 2026-01-28 EP claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
WO-2025040820-A1 ANTI-CD203C ANTIBODY CONJUGATES AND USES THEREOF GRANULAR THERAPEUTICS LIMITED (GB) 2025-02-27 WO claimed
CN-119300868-A Camptothecins compound and conjugate thereof, preparation method and application thereof 映恩生物科技(上海)有限公司 2025-01-10 CN claimed
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF IMMUNOGEN, INC. 2025-01-09 US claimed
CN-119053607-A Camptothecins compound and conjugate thereof, preparation method and application thereof 映恩生物科技(上海)有限公司 2024-11-29 CN claimed
CN-113769108-B Conjugates of cysteine engineered antibodies 伊缪诺金公司 2024-11-08 CN claimed
WO-2024193692-A1 LINKER AND USE THEREOF IN LIGAND DRUG CONJUGATE 映恩生物制药(苏州)有限公司 2024-09-26 WO claimed
CN-118681035-A Ligand drug conjugate and preparation method and application thereof 映恩生物制药(苏州)有限公司 2024-09-24 CN claimed
CN-106604927-B Cytotoxic benzodiazepine derivatives 伊缪诺金公司 2022-08-09 CN claimed
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2022-05-17 US claimed
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN SWITZERLAND GMBH (CH) 2022-04-14 US claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 EP claimed
EP-2601209-A1 GENOMICS OF ACTINOPLANES UTAHENSIS Bayer Intellectual Property GmbH (DE) 2013-06-12 EP claimed
WO-2012016960-A1 GENOMICS OF ACTINOPLANES UTAHENSIS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-02-09 WO claimed
EP-0254999-B1 ANTIBIOTIC A 42867 AND THE ADDITION SALTS THEREOF GRUPPO LEPETIT S.p.A. (IT) 1992-09-23 EP claimed
CN-85107903-A Produce the method for antibiotic A40926 complex and pure factors PA.PB.A.B. and B0 1987-05-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF DPP4 1262/4885MME 1501/4885ACE 1733/4885
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VIP, AREG, MIF DPP4 1262/4885MME 1501/4885ACE 1733/4885
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF GABRA6, GABRA2, GABRA1 DPP4 4358/4885MME 1946/4885ACE 4006/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG DPP4 2235/4885MME 961/4885ACE 2255/4885
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA DPP4 2000/4885MME 481/4885ACE 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.