SCHEMBL380600

SCHEMBL380600

C[C@H](N)C(=O)N[C@H](C)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.52
MME P08473 4/20 0.48
ACE P12821 1/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
CTRB1 P17538 5/20 0.42
DPP8 Q6V1X1 1/20 0.40
DPP7 Q9UHL4 1/20 0.40
SLC7A5 Q01650 1/20 0.40
LTA4H P09960 2/20 0.40
RAB9A P51151 1/20 0.39
PAX8 Q06710 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17545410 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL380599 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL5161799 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL29898350 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL9698824 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL574263 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL476353 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL159553 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
SCHEMBL159552 1.00 DPP4 (0.52) DPP4MMEACECPA1ACE2
Water SCHEMBL23711627 0.98 DPP4 (0.50) DPP4MMEACECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
WO-2025040820-A1 ANTI-CD203C ANTIBODY CONJUGATES AND USES THEREOF GRANULAR THERAPEUTICS LIMITED (GB) 2025-02-27 WO claimed
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF IMMUNOGEN, INC. 2025-01-09 US claimed
CN-113769108-B Conjugates of cysteine engineered antibodies 伊缪诺金公司 2024-11-08 CN claimed
US-20240226312-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA IMMUNOGEN, INC. (US) 2024-07-11 US claimed
EP-4374850-A2 METHODS OF PREVENTING METHIONINE OXIDATION IN IMMUNOCONJUGATES ImmunoGen, Inc. (US) 2024-05-29 EP claimed
US-20240165256-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER IMMUNOGEN INC (US) 2024-05-23 US claimed
US-11897961-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2024-02-13 US claimed
EP-4304660-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER ImmunoGen, Inc. (US) 2024-01-17 EP claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 EP claimed
WO-2020145776-A1 COMPOSITION FOR TARGETING MEDULLARY THYROID CANCER 연세대학교 산학협력단 2020-07-16 WO claimed
CN-108866103-A A kind of fermented soybean metabolin and its application 广州市仙婷贸易有限公司 2018-11-23 CN claimed
EP-3052135-A1 INHIBITORS OF METALLO-BETA-LACTAMASE (MBL) COMPRISING A ZINC CHELATING MOIETY Universitetet I Oslo (NO) 2016-08-10 EP claimed
WO-2015049546-A1 INHIBITORS OF METALLO-BETA-LACTAMASE (MBL) COMPRISING A ZINC CHELATING MOIETY UNIVERSITETET I OSLO (NO) 2015-04-09 WO claimed
EP-1147129-A4 SACCHARIDES LINKED TO COMPOUNDS THAT BIND CELL-SURFACE PEPTIDES OR PROTEINS UNIV PRINCETON (US) 2003-01-15 EP claimed
EP-1147129-A1 SACCHARIDES LINKED TO COMPOUNDS THAT BIND CELL-SURFACE PEPTIDES OR PROTEINS Princeton University (US) 2001-10-24 EP claimed
WO-2000042067-A1 SACCHARIDES LINKED TO COMPOUNDS THAT BIND CELL-SURFACE PEPTIDES OR PROTEINS PRINCETON UNIVERSITY (US) 2000-07-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF DPP4 1262/4885MME 1501/4885ACE 1733/4885
US-11897961-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA DPP4 2000/4885MME 481/4885ACE 2467/4885
US-20240165256-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER ADAM9, TMPRSS15, ADAM17 DPP4 466/4885MME 59/4885ACE 278/4885
US-20240226312-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA FOLR1, FOLR2, FRS2 DPP4 4488/4885MME 3187/4885ACE 4766/4885
US-20250011340-A1 BENZODIAZEPINE DERIVATIVES AND ANTIBODY CONJUGATES THEREOF GABRA6, GABRA2, GABRA1 DPP4 4358/4885MME 1946/4885ACE 4006/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG DPP4 2235/4885MME 961/4885ACE 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.