Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609979 | 0.94 | HMGCR (0.44) | HMGCRLMNAALDH1A1KDM4EGAA | |
| SCHEMBL16736891 | 0.89 | TYR (0.50) | HMGCRLMNAALDH1A1KDM4EGAA | |
| SCHEMBL10639901 | 0.85 | HMGCR (0.53) | HMGCRLMNAALOX5ESR1ESR2 | |
| SCHEMBL8764455 | 0.83 | HMGCR (0.52) | HMGCRLMNAALDH1A1KDM4EGAA | |
| SCHEMBL16736863 | 0.83 | HMGCR (0.52) | HMGCRLMNAALDH1A1KDM4EGAA | |
| SCHEMBL574139 | 0.83 | LMNA (0.48) | LMNAALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL23387409 | 0.81 | HMGCR (0.53) | HMGCRLMNAALDH1A1KDM4EALOX5 | |
| SCHEMBL6535477 | 0.81 | LMNA (0.50) | LMNAALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL13842565 | 0.81 | HMGCR (0.53) | HMGCRLMNAALDH1A1KDM4EGAA | |
| SCHEMBL16736876 | 0.80 | HMGCR (0.48) | HMGCRLMNAALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135297-A1 | AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION | ISP INVESTMENTS INC. (US) | 2014-05-15 | — | — | US | claimed |
| EP-2313026-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | Castle Beach, L.L.C. (US) | 2011-04-27 | — | — | EP | claimed |
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | Castle Beach, LLC (US) | 2010-02-18 | — | — | US | claimed |
| WO-2010019680-A1 | ACTIVE DELIVERY SYSTEM FORMULATIONS | HOMOLA ANDREW M (US) | 2010-02-18 | — | — | WO | claimed |
| US-20090214606-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | CIBA SPECIALTY CHEMICALS CORP. | 2009-08-27 | — | — | US | claimed |
| EP-1549731-B1 | CLEANING AND DISINFECTING COMPOSITION | RECKITT BENCKISER INC (US) | 2008-12-17 | — | — | EP | claimed |
| EP-1879457-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | Ciba Specialty Chemicals Holding, Inc. (CH) | 2008-01-23 | — | — | EP | claimed |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | CIBA SPECIALTY CHEMICALS CORP. | 2007-10-04 | — | — | US | claimed |
| WO-2006120135-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-11-16 | — | — | WO | claimed |
| US-20060093570-A1 | Surface treatment | RECKITT BENCKISER (UK) LIMITED (GB) | 2006-05-04 | — | — | US | claimed |
| US-20060034880-A1 | Cleaning and disinfecting composition | RECKITT BENCKISER INC (US) | 2006-02-16 | — | — | US | claimed |
| US-20050233930-A1 | Disinfectant cleaning compositions | RECKITT BENCKISER INC. (US) | 2005-10-20 | — | — | US | claimed |
| EP-1549730-A1 | DISINFECTANT CLEANING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2005-07-06 | — | — | EP | claimed |
| EP-1549731-A1 | CLEANING AND DISINFECTING COMPOSITION | Reckitt Benckiser Inc. (US) | 2005-07-06 | — | — | EP | claimed |
| EP-1537201-A1 | HARD SURFACE TREATING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2005-06-08 | — | — | EP | claimed |
| EP-0805672-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 2004-08-25 | — | — | EP | claimed |
| WO-2004035724-A1 | CLEANING AND DISINFECTING COMPOSITION | RECKITT BENCKISER INC (US) | 2004-04-29 | — | — | WO | claimed |
| WO-2004035723-A1 | DISINFECTANT CLEANING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-04-29 | — | — | WO | claimed |
| WO-2004024861-A1 | HARD SURFACE TREATING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-03-25 | — | — | WO | claimed |
| US-5665333-A | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth | PROVSEAL LLC | 1997-09-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040565-A1 | ACTIVE DELIVERY SYSTEMS FORMULATIONS | LIPA, MMP7, CTSA | HMGCR 429/4885LMNA 413/4885ALDH1A1 1412/4885 |
| US-20060034880-A1 | Cleaning and disinfecting composition | APOBEC3G, APOBEC3C, APOBEC3B | HMGCR 4827/4885LMNA 2556/4885ALDH1A1 4062/4885 |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | SIK2, SIK3, SIK1 | HMGCR 4315/4885LMNA 4300/4885ALDH1A1 4610/4885 |
| US-20090214606-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | ORAI3, PRF1, THPO | HMGCR 4157/4885LMNA 4072/4885ALDH1A1 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.