Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 5/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740488 | 0.84 | HSP90AA1 (0.57) | AGPAT2HSP90AA1HSP90AB1 | |
| SCHEMBL5741860 | 0.83 | MAPT (0.52) | AGPAT2HSP90AA1HSP90AB1 | |
| SCHEMBL5742562 | 0.80 | MAPT (0.53) | AGPAT2HSP90AA1HSP90AB1 | |
| SCHEMBL5740482 | 0.80 | ALOX15 (0.48) | AGPAT2HSP90AA1HSP90AB1 | |
| SCHEMBL5741907 | 0.79 | MCHR1 (0.44) | AGPAT2MCHR1PDPK1TLR8 | |
| SCHEMBL5740342 | 0.79 | AGPAT2 (0.59) | AGPAT2HSP90AA1HSP90AB1 | |
| SCHEMBL5741832 | 0.78 | AGPAT2 (0.46) | AGPAT2HSP90AA1HSP90AB1PDPK1 | |
| SCHEMBL5743121 | 0.78 | AGPAT2 (0.55) | AGPAT2HSP90AA1HSP90AB1 | |
| SCHEMBL5743256 | 0.78 | MCHR1 (0.59) | AGPAT2MCHR1TLR8 | |
| SCHEMBL5741580 | 0.77 | ACP1 (0.48) | AGPAT2MCHR1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |