Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.53 |
| ▸ | ENPEP | Q07075 | 8/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.48 |
| ▸ | CASP9 | P55211 | 3/20 | 0.48 |
| ▸ | CASP4 | P49662 | 1/20 | 0.48 |
| ▸ | CASP5 | P51878 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | GZMB | P10144 | 3/20 | 0.44 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20257260 | 1.00 | TASP1 (0.53) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL7067113 | 0.93 | TASP1 (0.62) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL23132679 | 0.93 | TASP1 (0.52) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL2381289 | 0.93 | TASP1 (0.52) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL20257131 | 0.93 | TASP1 (0.52) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL23133165 | 0.93 | TASP1 (0.52) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL23133164 | 0.93 | TASP1 (0.50) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL23924919 | 0.93 | TASP1 (0.52) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL4100803 | 0.91 | CASP1 (0.50) | TASP1ENPEPCASP1CASP3CASP9 | |
| SCHEMBL13194679 | 0.91 | CASP1 (0.50) | TASP1ENPEPCASP1CASP3CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11052154-B2 | Ras protein degradation inducing molecule and pharmaceutical composition | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-07-06 | — | — | US | disclosed |
| US-11007269-B2 | P53 degradation inducing molecule and pharmaceutical composition | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-05-18 | — | — | US | disclosed |
| US-10976306-B2 | Protein degradation inducing tag and usage thereof | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20210088504-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-03-25 | — | — | US | disclosed |
| US-20190314508-A1 | P53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2019-10-17 | — | — | US | disclosed |
| US-20180164289-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10976306-B2 | Protein degradation inducing tag and usage thereof | SENP8, SENP6, SENP7 | TASP1 1024/4885ENPEP 318/4885CASP1 1744/4885 |
| US-20190314508-A1 | P53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | TP53, TP53BP1, MDM2 | TASP1 1006/4885ENPEP 566/4885CASP1 919/4885 |
| US-11052154-B2 | Ras protein degradation inducing molecule and pharmaceutical composition | KRAS, G3BP1, NRAS | TASP1 960/4885ENPEP 864/4885CASP1 2718/4885 |
| US-20180164289-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | SENP8, SENP6, SENP7 | TASP1 1024/4885ENPEP 318/4885CASP1 1744/4885 |
| US-20210088504-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | SENP8, SENP6, SENP7 | TASP1 1024/4885ENPEP 318/4885CASP1 1744/4885 |
| US-11007269-B2 | P53 degradation inducing molecule and pharmaceutical composition | TP53, TP53BP1, MDM2 | TASP1 1006/4885ENPEP 566/4885CASP1 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.