SCHEMBL23133164

SCHEMBL23133164

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)O)NC(=O)[C@@H](NC(C)=O)C(C)C)C(=O)N[C@H](C=O)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.50
▸ CASP1 P29466 2/20 0.46
▸ CASP3 P42574 2/20 0.46
▸ CASP9 P55211 2/20 0.46
▸ CASP4 P49662 1/20 0.46
▸ CASP5 P51878 1/20 0.46
▸ CASP6 P55212 1/20 0.46
▸ CASP8 Q14790 1/20 0.46
▸ CASP10 Q92851 1/20 0.46
▸ GZMB P10144 3/20 0.44
▸ ENPEP Q07075 9/20 0.41
▸ CASP7 P55210 1/20 0.39
▸ MAGI3 Q5TCQ9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20257263 0.93 TASP1 (0.53) TASP1CASP1CASP3CASP9CASP4
SCHEMBL20257260 0.93 TASP1 (0.53) TASP1CASP1CASP3CASP9CASP4
SCHEMBL7067113 0.90 TASP1 (0.62) TASP1CASP1CASP3CASP9CASP4
SCHEMBL2381289 0.87 TASP1 (0.52) TASP1CASP1CASP3CASP9CASP4
SCHEMBL23133165 0.87 TASP1 (0.52) TASP1CASP1CASP3CASP9CASP4
SCHEMBL20257131 0.87 TASP1 (0.52) TASP1CASP1CASP3CASP9CASP4
SCHEMBL23924919 0.87 TASP1 (0.52) TASP1CASP1CASP3CASP9CASP4
SCHEMBL23132679 0.87 TASP1 (0.52) TASP1CASP1CASP3CASP9CASP4
SCHEMBL5746872 0.85 TASP1 (0.61) TASP1CASP1CASP3CASP9CASP4
SCHEMBL4100803 0.83 CASP1 (0.50) TASP1CASP1CASP3CASP9CASP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210088504-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2021-03-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210088504-A1 PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF SENP8, SENP6, SENP7 TASP1 1024/4885CASP1 1744/4885CASP3 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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