Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 3/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750532 | 0.78 | PDE2A (0.37) | SMN1; SMN2LMNAMAPK1HTTHPGD | |
| SCHEMBL5236413 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2LMNAMAPK1HTTPDE2A | |
| SCHEMBL5249517 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPK1HTTPDE2A | |
| SCHEMBL5622818 | 0.70 | ALDH1A1 (0.39) | HPGDALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4695582 | 0.68 | CSNK2A1 (0.39) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL4819849 | 0.68 | MBOAT4 (0.44) | PDE2AALDH1A1KMT2APOLB | |
| SCHEMBL3277093 | 0.66 | PTGES (0.40) | SMN1; SMN2LMNAMAPK1HTTPDE2A | |
| SCHEMBL8916197 | 0.66 | PDE2A (0.39) | SMN1; SMN2LMNAHTTHPGDPDE2A | |
| SCHEMBL4820465 | 0.66 | PDE2A (0.39) | SMN1; SMN2LMNAHTTHPGDPDE2A | |
| SCHEMBL4810439 | 0.66 | ALDH1A1 (0.42) | SMN1; SMN2LMNAMAPK1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199801-A1 | Heterobicyclic compounds used as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-07 | — | — | US | disclosed |
| EP-1620436-A1 | HETEROBICYCLIC COMPOUNDS USED AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004092175-A1 | HETEROBICYCLIC COMPOUNDS USED AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199801-A1 | Heterobicyclic compounds used as fungicides | CBR3, CBR1, CYP2A6 | SMN1; SMN2 2672/4885LMNA 1196/4885MAPK1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.