Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748565 | 0.82 | ALOX12 (0.45) | KDM4ESMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL5747136 | 0.81 | RIOK2 (0.46) | TRPV1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5746464 | 0.81 | TRPV1 (0.57) | TRPV1RAB9AHSD17B10 | |
| SCHEMBL5773999 | 0.81 | RIOK2 (0.42) | TRPV1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5777222 | 0.81 | RIOK2 (0.42) | TRPV1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5771528 | 0.81 | RIOK2 (0.42) | TRPV1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5749197 | 0.79 | KCNH3 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5750951 | 0.79 | KCNH3 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5748767 | 0.79 | KCNH3 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5914010 | 0.79 | MAPT (0.43) | TRPV1KDM4ERIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |