Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745314 | 0.87 | KDM4E (0.42) | ALOX12KDM4EGPR3TDP1L3MBTL1 | |
| SCHEMBL5746333 | 0.87 | KDM4E (0.42) | ALOX12KDM4EGPR3TDP1L3MBTL1 | |
| SCHEMBL5750072 | 0.87 | KDM4E (0.42) | ALOX12KDM4EGPR3TDP1L3MBTL1 | |
| SCHEMBL5750951 | 0.86 | KCNH3 (0.44) | HTTSMN1; SMN2KDM4EMAPK10GPR3 | |
| SCHEMBL5749197 | 0.86 | KCNH3 (0.44) | HTTSMN1; SMN2KDM4EMAPK10GPR3 | |
| SCHEMBL5748767 | 0.86 | KCNH3 (0.44) | HTTSMN1; SMN2KDM4EMAPK10GPR3 | |
| SCHEMBL5748693 | 0.82 | TLR8 (0.41) | HTTSMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL15834054 | 0.82 | NOS3 (0.50) | MEN1MAPK10GFERKMT2AGRM5 | |
| SCHEMBL5746344 | 0.81 | MME (0.41) | SMN1; SMN2KDM4ETDP1L3MBTL1NR3C2 | |
| SCHEMBL5779245 | 0.80 | MAPT (0.43) | KDM4EGPR3TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |