Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | KDM1A | O60341 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751946 | 0.85 | NPC1 (0.45) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635331 | 0.80 | KDM1A (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635334 | 0.80 | KDM1A (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL2635332 | 0.80 | KDM1A (0.65) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL4088795 | 0.77 | CPB1 (0.55) | KDM1AMAOAMAOBNPC1ALDH1A1 | |
| SCHEMBL4083721 | 0.77 | CPB1 (0.55) | KDM1AMAOAMAOBNPC1ALDH1A1 | |
| SCHEMBL12185088 | 0.76 | HRH3 (0.59) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL3545211 | 0.75 | KDM1A (0.60) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL3545210 | 0.75 | KDM1A (0.60) | HRH3KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL28697724 | 0.74 | KDM1A (0.62) | HRH3KDM1AMAOAMAOBRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660488-A1 | NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS | Warner-Lambert Company LLC (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20050065187-A1 | Novel antimicrobial aryloxazolidinone compounds | GORDEEV MIKHAIL FEDOROVICH (US) | 2005-03-24 | — | — | US | disclosed |
| WO-2005019214-A1 | NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050038086-A1 | Epothilone derivatives and methods for making and using the same | ASHLEY GARY (US) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065187-A1 | Novel antimicrobial aryloxazolidinone compounds | XDH, NQO1, MPO | HRH3 1868/4885KDM1A 2828/4885MAOA 144/4885 |
| US-20050038086-A1 | Epothilone derivatives and methods for making and using the same | EPOR, CCNA1, CCNY | HRH3 1304/4885KDM1A 2321/4885MAOA 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.