Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586638 | 0.89 | PTPN1 (0.46) | ALDH1A1KDM4EMAPTPTPN1TRPA1 | |
| SCHEMBL2832894 | 0.89 | AHR (0.41) | PTPN1CTNNB1AHRAPP | |
| SCHEMBL18586639 | 0.89 | PTPN1 (0.46) | ALDH1A1KDM4EMAPTPTPN1TRPA1 | |
| SCHEMBL25218117 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTPTPN1TRPA1 | |
| SCHEMBL1524953 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTCTNNB1LMNA | |
| SCHEMBL9035379 | 0.80 | TRPA1 (0.60) | ALDH1A1KDM4EMAPTTRPA1LMNA | |
| SCHEMBL9035381 | 0.80 | TRPA1 (0.60) | ALDH1A1KDM4EMAPTTRPA1LMNA | |
| SCHEMBL10477124 | 0.79 | FDPS (0.49) | CTNNB1APP | |
| SCHEMBL5750014 | 0.79 | THRB (0.59) | ALDH1A1KDM4EMAPT | |
| SCHEMBL7663462 | 0.79 | THRB (0.59) | ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1387841-B1 | NOVEL AZOLE OR TRIAZOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE THEREOF AS FUNGICIDES | AVENTIS PHARMA SA (FR) | 2006-03-08 | — | — | EP | disclosed |
| US-6946460-B2 | Azole or triazole derivatives, method for preparing same and use thereof as fungicides | AVENTIS PHARMA S.A. (FR) | 2005-09-20 | — | — | US | disclosed |
| US-20050043540-A1 | Novel azole or triazole derivatives, method for preparing same and use thereof as fungicides | AVENTIS PHARMA S. A, (FR) | 2005-02-24 | — | — | US | disclosed |
| US-20030187267-A1 | Novel 1,2,3,4-tetrahydroisoquinoline, their preparation method and their use as fungicides | AVENTIS PHARMA S.A. (FR) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043540-A1 | Novel azole or triazole derivatives, method for preparing same and use thereof as fungicides | CYP1A2, CYP1B1, CYP21A2 | ALDH1A1 410/4885KDM4E 2311/4885MAPT 3283/4885 |
| US-20030187267-A1 | Novel 1,2,3,4-tetrahydroisoquinoline, their preparation method and their use as fungicides | CYP1A1, CBR3, HAAO | ALDH1A1 203/4885KDM4E 1424/4885MAPT 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.