Mannitol Hexanitrate

Mannitol Hexanitrate

SCHEMBL57515

O=[N+]([O-])OC[C@@H](O[N+](=O)[O-])[C@@H](O[N+](=O)[O-])[C@H](O[N+](=O)[O-])[C@@H](CO[N+](=O)[O-])O[N+](=O)[O-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannitol Hexanitrate SCHEMBL220255 1.00 ALDH1A1 (0.36) ALDH1A1
SCHEMBL16541089 0.95 ALDH1A1 (0.36) ALDH1A1
Erythrityl Tetranitrate SCHEMBL119876 0.88 ALDH1A1 (0.40) ALDH1A1
Tetranitrin SCHEMBL613474 0.88 ALDH1A1 (0.40) ALDH1A1
Erythrityl Tetranitrate SCHEMBL1816345 0.88 ALDH1A1 (0.40) ALDH1A1
Tetranitrin SCHEMBL16541075 0.88 ALDH1A1 (0.40) ALDH1A1
SCHEMBL28671436 0.86 ALDH1A1 (0.30) ALDH1A1
SCHEMBL9470796 0.86 GSR (0.33)
SCHEMBL13714527 0.86
SCHEMBL13714555 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260110607-A1 TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES ALTI LLC (US) 2026-04-23 US claimed
US-12517047-B2 Transport and detection of explosive samples ALTI LLC (US) 2026-01-06 US claimed
US-20250237601-A1 TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES ALTI LLC 2025-07-24 US claimed
WO-2024240321-A1 AUTOMATED REVOLVING COCOA FERMENTER GARCIA POLANCO AYBAN CARLOS (DO) 2024-11-28 WO claimed
EP-3044190-B1 BURN RATE MODIFIER THALES AUSTRALIA LTD (AU) 2024-07-03 EP claimed
US-20230355500-A1 TOPICAL COMPOSITION LILIGER LTD (IL) 2023-11-09 US claimed
WO-2023183932-A2 MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) NEW YORK UNIVERSITY (US) 2023-09-28 WO claimed
US-20220082003-A1 TEMPERATURE REACTIVE ACOUSTIC PARTICLES FOR MAPPING FRACTURES US ENERGY (US) 2022-03-17 US claimed
EP-3485908-B1 THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS MEREO BIOPHARMA 5 INC (US) 2021-08-18 EP claimed
US-20200276145-A1 REDUCING SIDE EFFECTS OF SHORT ACTING NO DONORS G. POHL-BOSKAMP GMBH & CO. KG (DE) 2020-09-03 US claimed
EP-0104877-A2 Organic nitrate drug mixtures resistant to detonation by fire ICI AMERICAS INC. (US) 1984-04-04 EP claimed
EP-0069385-A2 Use of eucalyptol for enhancing skin permeation of bioaffecting agents MERCK & CO. INC. (US) 1983-01-12 EP claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
EP-0036138-A2 Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide MERCK & CO. INC. (US) 1981-09-23 EP claimed
US-4271747-A Fastening element with a cavity containing an explosive charge DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-06-09 US claimed
US-4112115-A Therapy of leg muscle cramps COGHLAN CHARLES C 1978-09-05 US claimed
US-4025591-A ACRYLIC ESTER CURING MONOMER, ORGANIC PEROXIDE CATALYST JET RESEARCH CENTER, INC. (US) 1977-05-24 US claimed
US-4008719-A Osmotic system having laminar arrangement for programming delivery of active agent ALZA CORPORATION (US) 1977-02-22 US claimed
US-3993072-A Microporous drug delivery device ALZA CORPORATION (US) 1976-11-23 US claimed
US-3957550-A EXPLOSIVES, LIQUID FUELS, OXIDIZERS THIOKOL CORPORATION (US) 1976-05-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260110607-A1 TRANSPORT AND DETECTION OF EXPLOSIVE SAMPLES WITH MINIMIZED FALSE POSITIVES TES, TNPO1, SLC2A1 ALDH1A1 4406/4885
US-20230355500-A1 TOPICAL COMPOSITION NOS1, NOS3, NOS2 ALDH1A1 2053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.