Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259869 | 0.80 | MAPT (0.36) | HPGDGPR84 | |
| SCHEMBL9958782 | 0.74 | GPR84 (0.33) | GPR84 | |
| SCHEMBL8132104 | 0.67 | KDM4E (0.34) | HPGD | |
| SCHEMBL5001270 | 0.63 | CYP1A2 (0.33) | — | |
| SCHEMBL28006187 | 0.61 | — | — | |
| SCHEMBL30626777 | 0.61 | — | — | |
| SCHEMBL9673747 | 0.58 | ALDH1A1 (0.44) | HPGD | |
| SCHEMBL11074497 | 0.58 | ALDH1A1 (0.41) | HPGD | |
| SCHEMBL2536697 | 0.58 | TRPA1 (0.36) | — | |
| SCHEMBL19026492 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687314-A1 | PREPARATION OF 1-AZA-2-OXA-DIBENZO [e,h] AZULENES AND THEIR USE FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS | Pliva-Istrazivacki Institut D.D.O. (HR) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049623-A1 | PREPARATION OF 1-AZA-2-OXA-DIBENZO[e,h]AZULENES AND THEIR USE FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-06-02 | — | — | WO | disclosed |