Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752857 | 0.87 | ALDH1A1 (0.64) | TXNRD1CYP1A2CYP2C9MAPTALDH1A1 | |
| SCHEMBL2421463 | 0.87 | ALDH1A1 (0.64) | TXNRD1CYP1A2CYP2C9MAPTALDH1A1 | |
| SCHEMBL30435070 | 0.85 | SIRT6 (0.54) | TXNRD1MAPTALDH1A1MAPK1POLB | |
| SCHEMBL5753875 | 0.85 | SIRT6 (0.54) | TXNRD1MAPTALDH1A1MAPK1POLB | |
| SCHEMBL20502406 | 0.81 | TXNRD1 (0.49) | TXNRD1CYP1A2CYP2C9MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5220902 | 0.81 | TXNRD1 (0.49) | TXNRD1MAPTALDH1A1MAPK1POLB | |
| SCHEMBL21627197 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP2C9MAPTALDH1A1MAPK1 | |
| SCHEMBL3239219 | 0.79 | CYP1A2 (0.59) | TXNRD1CYP1A2CYP2C9MAPTALDH1A1 | |
| SCHEMBL6509373 | 0.79 | TXNRD1 (0.47) | TXNRD1MAPTALDH1A1MAPK1POLB | |
| SCHEMBL14334303 | 0.79 | TXNRD1 (0.51) | TXNRD1MAPTALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016006921-A1 | ACUTE MYELOID LEUKEMIA TARGETED THERAPEUTIC AGENT WITH REDUCED DRUG SIDE EFFECTS | 한국과학기술연구원 | 2016-01-14 | — | — | WO | disclosed |
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | disclosed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | disclosed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | disclosed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | KRT18, DSP, DPYD | TXNRD1 1135/4885CYP1A2 1721/4885CYP2C9 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.