Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 16/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5220902 | 0.85 | TXNRD1 (0.49) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL2421463 | 0.82 | ALDH1A1 (0.64) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL5752857 | 0.82 | ALDH1A1 (0.64) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL2689490 | 0.81 | TDP1 (0.52) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL30435070 | 0.80 | SIRT6 (0.54) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL5753875 | 0.80 | SIRT6 (0.54) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL5754304 | 0.79 | TXNRD1 (0.57) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL14334303 | 0.79 | TXNRD1 (0.51) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL5219253 | 0.78 | TXNRD1 (0.47) | TXNRD1MAPTMAPK1ALDH1A1POLB | |
| SCHEMBL3435667 | 0.77 | TXNRD1 (0.47) | TXNRD1MAPTMAPK1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095339-A1 | DICYANOPYRROLIDINES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-10-13 | — | — | WO | disclosed |