Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754117 | 0.92 | CACNA1B (0.42) | RENKLK5ATMKMT2A | |
| SCHEMBL5758360 | 0.92 | PSMB1 (0.45) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL5756667 | 0.89 | REN (0.38) | RENATMKMT2A | |
| SCHEMBL5756949 | 0.86 | REN (0.37) | RENKLK5 | |
| SCHEMBL5759035 | 0.86 | CACNA1B (0.49) | KLK5ATMKMT2A | |
| SCHEMBL5753527 | 0.86 | NPC1 (0.39) | KMT2A | |
| SCHEMBL5756196 | 0.86 | CACNA1B (0.38) | KLK5ATMKMT2A | |
| SCHEMBL5754795 | 0.85 | CACNA1B (0.43) | KLK5ATMKMT2A | |
| SCHEMBL5754050 | 0.84 | NPC1 (0.37) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL5756303 | 0.84 | KMT2A (0.37) | ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |