Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756667 | 0.86 | REN (0.38) | REN | |
| SCHEMBL5754577 | 0.86 | REN (0.39) | RENKLK5 | |
| SCHEMBL5754117 | 0.86 | CACNA1B (0.42) | RENKLK5LMNA | |
| SCHEMBL5758360 | 0.84 | PSMB1 (0.45) | REN | |
| SCHEMBL5754373 | 0.83 | MAPT (0.32) | RENCTSLCTSSCTSKKDM4E | |
| SCHEMBL5755652 | 0.82 | GPR119 (0.38) | RENKLK5 | |
| SCHEMBL5756196 | 0.80 | CACNA1B (0.38) | KLK5LMNAHPGD | |
| SCHEMBL5754050 | 0.80 | NPC1 (0.37) | RENCTSS | |
| SCHEMBL5753257 | 0.79 | MEN1 (0.43) | LMNA | |
| SCHEMBL5756303 | 0.78 | KMT2A (0.37) | KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |