Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754577 | 0.89 | REN (0.39) | RENATMKMT2A | |
| SCHEMBL5754117 | 0.89 | CACNA1B (0.42) | RENCACNA1BATMKMT2A | |
| SCHEMBL5755360 | 0.88 | LMNA (0.34) | KMT2A | |
| SCHEMBL5758360 | 0.87 | PSMB1 (0.45) | RENPTPN1CACNA1B | |
| SCHEMBL5756338 | 0.87 | CACNA1B (0.40) | RENPTPN1CACNA1BATMKMT2A | |
| SCHEMBL5756949 | 0.86 | REN (0.37) | REN | |
| SCHEMBL5754504 | 0.86 | ACKR3 (0.32) | KMT2A | |
| SCHEMBL5754736 | 0.86 | CACNA1B (0.40) | RENCACNA1BATMKMT2A | |
| SCHEMBL5756196 | 0.83 | CACNA1B (0.38) | PTPN1CACNA1BATMKMT2A | |
| SCHEMBL5754050 | 0.82 | NPC1 (0.37) | RENCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |