Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 11/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754577 | 0.92 | REN (0.39) | PSMB1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL5754117 | 0.90 | CACNA1B (0.42) | RENCACNA1B | |
| SCHEMBL5754050 | 0.89 | NPC1 (0.37) | PSMB1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL5756667 | 0.87 | REN (0.38) | RENPTPN1CACNA1B | |
| SCHEMBL5758199 | 0.86 | CACNA1B (0.43) | PSMB1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL5756949 | 0.84 | REN (0.37) | REN | |
| SCHEMBL5756196 | 0.84 | CACNA1B (0.38) | PTPN1CACNA1B | |
| SCHEMBL5756531 | 0.83 | HTR2C (0.40) | PSMB1PSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL5756303 | 0.82 | KMT2A (0.37) | PTPN1CACNA1B | |
| SCHEMBL5756321 | 0.80 | CACNA1B (0.51) | PSMB8RENCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |