Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 13/20 | 0.71 |
| ▸ | PRKACA | P17612 | 3/20 | 0.71 |
| ▸ | PRKACG | P22612 | 3/20 | 0.71 |
| ▸ | PRKACB | P22694 | 3/20 | 0.71 |
| ▸ | PIM1 | P11309 | 2/20 | 0.71 |
| ▸ | PRKCB | P05771 | 12/20 | 0.71 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.71 |
| ▸ | GSK3B | P49841 | 6/20 | 0.71 |
| ▸ | PRKCH | P24723 | 3/20 | 0.71 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.71 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.71 |
| ▸ | CDK1 | P06493 | 3/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.71 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.71 |
| ▸ | PRKCG | P05129 | 3/20 | 0.71 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326609 | 0.87 | PRKACA (0.69) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL8245376 | 0.87 | CAMK2D (0.69) | PRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL8239373 | 0.86 | PRKACA (0.71) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL7057981 | 0.83 | PRKCA (1.00) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| Gf-109203 SCHEMBL29353725 | 0.83 | PRKACA (1.00) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| Gf-109203 SCHEMBL338086 | 0.83 | PRKACA (1.00) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| Hydrochloric Acid SCHEMBL8154146 | 0.82 | PRKCA (0.98) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL3774309 | 0.82 | PRKCA (0.65) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| Gf-109203 SCHEMBL29534077 | 0.82 | PRKACA (0.98) | PRKCAPRKACAPRKACGPRKACBPIM1 | |
| Gf-109203 SCHEMBL1199513 | 0.82 | PRKACA (0.98) | PRKCAPRKACAPRKACGPRKACBPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008514-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | GEORGETOWN UNIVERSITY (US) | 2007-01-18 | — | — | WO | disclosed |
| EP-1362047-B1 | INDAZOLYL-SUBSTITUTED PYRROLINE COMPOUNDS AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-05-17 | — | — | EP | disclosed |