Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 5/20 | 0.71 |
| ▸ | PRKACG | P22612 | 5/20 | 0.71 |
| ▸ | PRKACB | P22694 | 5/20 | 0.71 |
| ▸ | CDK4 | P11802 | 3/20 | 0.71 |
| ▸ | CCND1 | P24385 | 3/20 | 0.71 |
| ▸ | GSK3B | P49841 | 4/20 | 0.55 |
| ▸ | PRKCA | P17252 | 3/20 | 0.55 |
| ▸ | PRKCB | P05771 | 2/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.53 |
| ▸ | PIM1 | P11309 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8245376 | 0.87 | CAMK2D (0.69) | PRKACAPRKACGPRKACBCAMK2DPIM1 | |
| SCHEMBL5326609 | 0.87 | PRKACA (0.69) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL5755241 | 0.86 | PRKCA (0.71) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL7059398 | 0.83 | PIM1 (0.75) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL9148747 | 0.83 | PRKACA (1.00) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| Hydrochloric Acid SCHEMBL8163111 | 0.82 | PRKACA (0.74) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL5333204 | 0.81 | CDK2 (0.71) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL5459193 | 0.77 | CDK4 (0.56) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL4684095 | 0.77 | CAMK2D (0.77) | PRKACAPRKACGPRKACBCDK4CCND1 | |
| SCHEMBL9086181 | 0.74 | PRKACA (0.82) | PRKACAPRKACGPRKACBCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008514-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | GEORGETOWN UNIVERSITY (US) | 2007-01-18 | — | — | WO | disclosed |