Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 17/20 | 0.69 |
| ▸ | PRKACA | P17612 | 1/20 | 0.69 |
| ▸ | PRKACG | P22612 | 1/20 | 0.69 |
| ▸ | PRKACB | P22694 | 1/20 | 0.69 |
| ▸ | PIM1 | P11309 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5326609 | 0.90 | PRKACA (0.69) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL8239373 | 0.87 | PRKACA (0.71) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL5755241 | 0.87 | PRKCA (0.71) | PRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL1680137 | 0.82 | CAMK2D (1.00) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL1942352 | 0.81 | CAMK2D (1.00) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL29438694 | 0.81 | CAMK2D (1.00) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL5333204 | 0.81 | CDK2 (0.71) | PRKACAPRKACGPRKACBPIM1 | |
| Hydrochloric Acid SCHEMBL16371182 | 0.81 | CAMK2D (0.98) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| Hydrochloric Acid SCHEMBL8162861 | 0.80 | CAMK2D (0.98) | CAMK2DPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL5459193 | 0.80 | CDK4 (0.56) | PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008514-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | GEORGETOWN UNIVERSITY (US) | 2007-01-18 | — | — | WO | disclosed |