Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | PNLIP | P16233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755085 | 0.93 | SMN1; SMN2 (0.40) | HPGDGPR88MEN1KMT2AALDH1A1 | |
| SCHEMBL5753527 | 0.88 | NPC1 (0.39) | HPGDKMT2ACACNA1BPNLIPALDH1A1 | |
| SCHEMBL5754702 | 0.82 | CACNA1B (0.34) | CACNA1BPNLIPALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5754577 | 0.81 | REN (0.39) | KMT2A | |
| SCHEMBL5756749 | 0.80 | POLB (0.41) | HPGDKMT2ACACNA1BPNLIPALDH1A1 | |
| SCHEMBL5755208 | 0.80 | CACNA1B (0.36) | HPGDCACNA1BPNLIPALDH1A1HTT | |
| SCHEMBL5755403 | 0.79 | CACNA1B (0.40) | CACNA1B | |
| SCHEMBL5753832 | 0.79 | CACNA1B (0.36) | CACNA1BPNLIPHRH3NPY5RCTSS | |
| SCHEMBL5754438 | 0.78 | CACNA1B (0.51) | CACNA1BPNLIPALDH1A1NPY5RCTSS | |
| SCHEMBL5759035 | 0.76 | CACNA1B (0.49) | MEN1KMT2ACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |