Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753729 | 0.93 | ALDH1A1 (0.36) | CACNA1BPNLIPNPC1ALDH1A1HTT | |
| SCHEMBL5753527 | 0.89 | NPC1 (0.39) | CACNA1BPNLIPNPC1ALDH1A1MAPT | |
| SCHEMBL5755208 | 0.88 | CACNA1B (0.36) | CACNA1BPNLIPNPC1ALDH1A1MAPT | |
| SCHEMBL5753832 | 0.82 | CACNA1B (0.36) | CACNA1BPNLIPNPC1NPY5RITGB1 | |
| SCHEMBL5755571 | 0.82 | HPGD (0.36) | CACNA1BPNLIPALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5755403 | 0.81 | CACNA1B (0.40) | CACNA1B | |
| SCHEMBL5756749 | 0.81 | POLB (0.41) | CACNA1BPNLIPNPC1ALDH1A1HTT | |
| SCHEMBL5757143 | 0.81 | ALDH1A1 (0.35) | CACNA1BALDH1A1 | |
| SCHEMBL5754339 | 0.81 | ALDH1A1 (0.35) | CACNA1BALDH1A1 | |
| SCHEMBL5756531 | 0.81 | HTR2C (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |